Colorectal cancer (CRC) has emerged as the second most common cancer and the second leading cause of cancer death in Hong Kong. Surgery still remains the mainstay of curative treatment for CRC. However, about 50% of patients are diagnosed at more advanced stages and require further multimodal treatment. Management of advanced rectal cancer is even more complicated, and judicious use of preoperative chemoradiation is often needed to increase resectability rate and avoid the need for a permanent stoma. In the New Territories East Cluster (NTEC), we have established a Lower Gastrointestinal Cancer (LGIC) Multidisciplinary Team (MDT) consisting of different healthcare professionals and academics to deliver a highly efficient, evidence-based, personalised, and patient-centred care to our CRC patients. Through pioneering advances in minimally invasive surgery, cancer diagnostics, oncological service, and cancer-related research, the NTEC LGIC MDT is committed to provide the best care possible to our CRC patients with passion and professionalism. In this lecture, I will share with the audience our multidisciplinary approach for CRC in NTEC.